Prolongation of metallothionein induction combats Aß and α-synuclein toxicity in aged transgenic Caenorhabditis elegans

Neurodegenerative disorders (ND) like Alzheimer's (AD), Parkinson's (PD), Huntington's or Prion diseases share similar pathological features. They are all age dependent and are often associated with disruptions in analogous metabolic processes such as protein aggregation and oxidative...

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Main Authors: Pretsch, D, Rollinger, JM, Schmid, A, Genov, M, Wöhrer, T, Krenn, L, Moloney, M, Kasture, A, Hummel, T, Pretsch, A
Format: Journal article
Jezik:English
Izdano: Nature Research 2020