Mechanistic studies on a Cu-catalyzed asymmetric allylic al-kylation with cyclic racemic starting materials

Mechanistic studies on Cu-catalysed asymmetric additions of alkylzirconocene nucleophiles to racemic allylic halide electrophiles were conducted using a combination of isotopic labelling, NMR spectroscopy, kinetic modeling, structure-activity relationships and new reaction development. Kinetic and d...

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Autori principali: Rideau, E, You, H, Sidera, M, Claridge, T, Fletcher, S
Natura: Journal article
Pubblicazione: American Chemical Society 2017