Single DNA rotaxanes of a transmembrane pore protein.
Threading a molecular needle: An α-hemolysin transmembrane pore can be threaded in a desired orientation by DNA-poly(ethylene glycol) (DNA-PEG) hybrid strands to yield functional rotaxanes (see figure). The single-molecule rotaxanes are stable and have a reversible two-state switching capacity that...
Main Authors: | , , , , |
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Format: | Journal article |
Language: | English |
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2004
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_version_ | 1826262767705784320 |
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author | Sánchez-Quesada, J Saghatelian, A Cheley, S Bayley, H Ghadiri, MR |
author_facet | Sánchez-Quesada, J Saghatelian, A Cheley, S Bayley, H Ghadiri, MR |
author_sort | Sánchez-Quesada, J |
collection | OXFORD |
description | Threading a molecular needle: An α-hemolysin transmembrane pore can be threaded in a desired orientation by DNA-poly(ethylene glycol) (DNA-PEG) hybrid strands to yield functional rotaxanes (see figure). The single-molecule rotaxanes are stable and have a reversible two-state switching capacity that depends on the applied potential, orientation, and method of threading and capture used. |
first_indexed | 2024-03-06T19:41:17Z |
format | Journal article |
id | oxford-uuid:20c0cb4f-4852-4676-8ea3-667fe54c091b |
institution | University of Oxford |
language | English |
last_indexed | 2024-03-06T19:41:17Z |
publishDate | 2004 |
record_format | dspace |
spelling | oxford-uuid:20c0cb4f-4852-4676-8ea3-667fe54c091b2022-03-26T11:29:19ZSingle DNA rotaxanes of a transmembrane pore protein.Journal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:20c0cb4f-4852-4676-8ea3-667fe54c091bEnglishSymplectic Elements at Oxford2004Sánchez-Quesada, JSaghatelian, ACheley, SBayley, HGhadiri, MRThreading a molecular needle: An α-hemolysin transmembrane pore can be threaded in a desired orientation by DNA-poly(ethylene glycol) (DNA-PEG) hybrid strands to yield functional rotaxanes (see figure). The single-molecule rotaxanes are stable and have a reversible two-state switching capacity that depends on the applied potential, orientation, and method of threading and capture used. |
spellingShingle | Sánchez-Quesada, J Saghatelian, A Cheley, S Bayley, H Ghadiri, MR Single DNA rotaxanes of a transmembrane pore protein. |
title | Single DNA rotaxanes of a transmembrane pore protein. |
title_full | Single DNA rotaxanes of a transmembrane pore protein. |
title_fullStr | Single DNA rotaxanes of a transmembrane pore protein. |
title_full_unstemmed | Single DNA rotaxanes of a transmembrane pore protein. |
title_short | Single DNA rotaxanes of a transmembrane pore protein. |
title_sort | single dna rotaxanes of a transmembrane pore protein |
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