Single DNA rotaxanes of a transmembrane pore protein.

Threading a molecular needle: An α-hemolysin transmembrane pore can be threaded in a desired orientation by DNA-poly(ethylene glycol) (DNA-PEG) hybrid strands to yield functional rotaxanes (see figure). The single-molecule rotaxanes are stable and have a reversible two-state switching capacity that...

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Detalles Bibliográficos
Main Authors: Sánchez-Quesada, J, Saghatelian, A, Cheley, S, Bayley, H, Ghadiri, MR
Formato: Journal article
Idioma:English
Publicado: 2004