Single DNA rotaxanes of a transmembrane pore protein.

Single DNA rotaxanes of a transmembrane pore protein.

Threading a molecular needle: An α-hemolysin transmembrane pore can be threaded in a desired orientation by DNA-poly(ethylene glycol) (DNA-PEG) hybrid strands to yield functional rotaxanes (see figure). The single-molecule rotaxanes are stable and have a reversible two-state switching capacity that...

Full description

Bibliographic Details
Main Authors:	Sánchez-Quesada, J, Saghatelian, A, Cheley, S, Bayley, H, Ghadiri, MR
Format:	Journal article
Language:	English
Published:	2004

Similar Items

A functional protein pore with a "retro" transmembrane domain.
by: Cheley, S, et al.
Published: (1999)

Electroosmotic enhancement of the binding of a neutral molecule to a transmembrane pore.
by: Gu, L, et al.
Published: (2003)

Properties of Bacillus cereus hemolysin II: a heptameric transmembrane pore.
by: Miles, G, et al.
Published: (2002)

Structure of staphylococcal alpha-hemolysin, a heptameric transmembrane pore.
by: Song, L, et al.
Published: (1996)

Engineered transmembrane pores.
by: Ayub, M, et al.
Published: (2016)

Reversal of charge selectivity in transmembrane protein pores by using noncovalent molecular adapters.
by: Gu, L, et al.
Published: (2000)

Engineering a dimeric transmembrane protein nanoconduit
by: Mantri, S, et al.
Published: (2012)

Subunit stoichiometry of staphylococcal alpha-hemolysin in crystals and on membranes: a heptameric transmembrane pore.
by: Gouaux, J, et al.
Published: (1994)

Location of a constriction in the lumen of a transmembrane pore by targeted covalent attachment of polymer molecules.
by: Movileanu, L, et al.
Published: (2001)

Detecting protein analytes that modulate transmembrane movement of a polymer chain within a single protein pore.
by: Movileanu, L, et al.
Published: (2000)

Single protein pores containing molecular adapters at high temperatures.
by: Kang, X, et al.
Published: (2005)

Single-molecule investigation of directional transport through a bacterial transmembrane pore
by: Lee, S, et al.
Published: (2017)

Redirecting pore assembly of staphylococcal α-hemolysin by protein engineering
by: Koo, S, et al.
Published: (2019)

Partitioning of individual flexible polymers into a nanoscopic protein pore.
by: Movileanu, L, et al.
Published: (2003)

A protein pore with a single polymer chain tethered within the lumen
by: Howorka, S, et al.
Published: (2000)

CHANNELS WITH SINGLE TRANSMEMBRANE SEGMENTS
by: Bayley, H
Published: (1994)

An engineered dimeric protein pore that spans adjacent lipid bilayers.
by: Mantri, S, et al.
Published: (2013)

Subunit composition of a bicomponent toxin: staphylococcal leukocidin forms an octameric transmembrane pore.
by: Miles, G, et al.
Published: (2002)

Probing distance and electrical potential within a protein pore with tethered DNA.
by: Howorka, S, et al.
Published: (2002)

BIOL 151-Real-time observation of stepwise DNA primer extension at the single-molecule level
by: Chu, J, et al.
Published: (2008)

Water in transmembrane pores: Simulation studies.
by: Sansom, M, et al.
Published: (2001)

Surface labeling of key residues during assembly of the transmembrane pore formed by staphylococcal alpha-hemolysin.
by: Krishnasastry, M, et al.
Published: (1994)

Genetically engineered metal ion binding sites on the outside of a Channel's transmembrane beta-barrel.
by: Kasianowicz, J, et al.
Published: (1999)

An engineered ClyA nanopore detects folded target proteins by selective external association and pore entry.
by: Soskine, M, et al.
Published: (2012)

Tumor protease-activated, pore-forming toxins from a combinatorial library.
by: Panchal, R, et al.
Published: (1996)

Simultaneous measurement of ionic current and fluorescence from single protein pores.
by: Heron, A, et al.
Published: (2009)

Temperature-responsive protein pores.
by: Jung, Y, et al.
Published: (2006)

Stochastic sensing with protein pores
by: Bayley, H, et al.
Published: (2000)

Interactions of peptides with a protein pore.
by: Movileanu, L, et al.
Published: (2005)

A photogenerated pore-forming protein.
by: Chang, C, et al.
Published: (1995)

Rapid Assembly of a Multimeric Membrane Protein Pore Observed by Single Molecule Fluorescence
by: Cronin, B, et al.
Published: (2012)

Molecular architecture of a toxin pore: a 15-residue sequence lines the transmembrane channel of staphylococcal alpha-toxin.
by: Valeva, A, et al.
Published: (1996)

The internal cavity of the staphylococcal alpha-hemolysin pore accommodates approximately 175 exogenous amino acid residues.
by: Jung, Y, et al.
Published: (2005)

Assaying nanogram amounts of dilute protein.
by: Cheley, S, et al.
Published: (1991)

Single molecule studies of seven transmembrane domain proteins
by: Berthoumieu, O
Published: (2011)

Permeation of styryl dyes through nanometer-scale pores in membranes.
by: Wu, Y, et al.
Published: (2011)

Spontaneous oligomerization of a staphylococcal alpha-hemolysin conformationally constrained by removal of residues that form the transmembrane beta-barrel.
by: Cheley, S, et al.
Published: (1997)

Synthesis of a cyclodextrin azo dye [3]rotaxane as a single isomer
by: Craig, MR, et al.
Published: (1999)

Rapid assembly of a multimeric membrane protein pore.
by: Thompson, JR, et al.
Published: (2011)

Water nanoconfined in a hydrophobic pore: molecular dynamics simulations of transmembrane protein 175 and the influence of water models
by: Lynch, CI, et al.
Published: (2021)