Legacy of the influenza pandemic 1918: The host T cell response
<p>The influenza virus was instrumental in unravelling critical aspects of the antiviral T lymphocyte mediated immune response. A major finding was the demonstration that CD8 T lymphocytes recognize short viral peptides presented by class I molecules of the major histocompatibility complex. St...
Main Author: | |
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Format: | Journal article |
Language: | English |
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Elsevier
2018
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_version_ | 1797057779239747584 |
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author | McMichael, A |
author_facet | McMichael, A |
author_sort | McMichael, A |
collection | OXFORD |
description | <p>The influenza virus was instrumental in unravelling critical aspects of the antiviral T lymphocyte mediated immune response. A major finding was the demonstration that CD8 T lymphocytes recognize short viral peptides presented by class I molecules of the major histocompatibility complex. Studies of influenza specific T cells have also led to an understanding of their important role in recovery from influenza virus infection in humans.</p> |
first_indexed | 2024-03-06T19:41:17Z |
format | Journal article |
id | oxford-uuid:20c1096e-31c2-4c46-96ad-361c0014aafd |
institution | University of Oxford |
language | English |
last_indexed | 2024-03-06T19:41:17Z |
publishDate | 2018 |
publisher | Elsevier |
record_format | dspace |
spelling | oxford-uuid:20c1096e-31c2-4c46-96ad-361c0014aafd2022-03-26T11:29:19ZLegacy of the influenza pandemic 1918: The host T cell responseJournal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:20c1096e-31c2-4c46-96ad-361c0014aafdEnglishSymplectic Elements at OxfordElsevier2018McMichael, A<p>The influenza virus was instrumental in unravelling critical aspects of the antiviral T lymphocyte mediated immune response. A major finding was the demonstration that CD8 T lymphocytes recognize short viral peptides presented by class I molecules of the major histocompatibility complex. Studies of influenza specific T cells have also led to an understanding of their important role in recovery from influenza virus infection in humans.</p> |
spellingShingle | McMichael, A Legacy of the influenza pandemic 1918: The host T cell response |
title | Legacy of the influenza pandemic 1918: The host T cell response |
title_full | Legacy of the influenza pandemic 1918: The host T cell response |
title_fullStr | Legacy of the influenza pandemic 1918: The host T cell response |
title_full_unstemmed | Legacy of the influenza pandemic 1918: The host T cell response |
title_short | Legacy of the influenza pandemic 1918: The host T cell response |
title_sort | legacy of the influenza pandemic 1918 the host t cell response |
work_keys_str_mv | AT mcmichaela legacyoftheinfluenzapandemic1918thehosttcellresponse |