Recurrent activating ACVR1 mutations in diffuse intrinsic pontine glioma

Recurrent activating ACVR1 mutations in diffuse intrinsic pontine glioma

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Diffuse intrinsic pontine gliomas (DIPGs) are highly infiltrative malignant glial neoplasms of the ventral pons that, due to their location within the brain, are unsuitable for surgical resection and consequently have a universally dismal clinical outcome. The median survival time is 9-12 months, wi...

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Dades bibliogràfiques
Autors principals: Taylor, K, Mackay, A, Truffaux, N, Butterfield, Y, Morozova, O, Philippe, C, Castel, D, Grasso, C, Vinci, M, Carvalho, D, Carcaboso, A, de Torres, C, Cruz, O, Mora, J, Entz-Werle, N, Ingram, W, Monje, M, Hargrave, D, Bullock, A, Puget, S, Yip, S, Jones, C, Grill, J
Format: Journal article
Idioma:English
Publicat: Nature Publishing Group 2014
Matèries:
Medical Sciences
Oncology
Clinical genetics
Genetics (medical sciences)
Life Sciences
Neuroscience

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