EGF receptor/Rolled MAP kinase signalling protects cells against activated Armadillo in the Drosophila eye.

EGF receptor/Rolled MAP kinase signalling protects cells against activated Armadillo in the Drosophila eye.

beta-catenin/Armadillo are transcriptional co-activators that mediate Wnt signalling in normal development. Activated forms of beta-catenin are oncogenic. We have constructed mutant forms of Drosophila Armadillo which correspond to common human oncogenic mutations, and find them to activate Armadill...

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Dettagli Bibliografici
Autori principali:	Freeman, M, Bienz, M
Natura:	Journal article
Lingua:	English
Pubblicazione:	2001

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