Setting research priorities to improve global newborn health and prevent stillbirths by 2025.
In 2013, an estimated 2.8 million newborns died and 2.7 million were stillborn. A much greater number suffer from long term impairment associated with preterm birth, intrauterine growth restriction, congenital anomalies, and perinatal or infectious causes. With the approaching deadline for the achie...
| المؤلفون الرئيسيون: | , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , |
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| التنسيق: | Journal article |
| اللغة: | English |
| منشور في: |
Edinburgh University Global Health Society
2016
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| _version_ | 1826262772503019520 |
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| author | Yoshida, S Martines, J Lawn, J Wall, S Souza, J Rudan, I Cousens, S Aaby, P Adam, I Adhikari, R Ambalavanan, N Arifeen, S Aryal, D Asiruddin, S Baqui, A Barros, A Benn, C Bhandari, V Bhatnagar, S Bhattacharya, S Bhutta, Z Black, R Blencowe, H Bose, C Brown, J Bührer, C Carlo, W Cecatti, J Cheung, P Clark, R Colbourn, T Conde-Agudelo, A Corbett, E Czeizel, A Das, A Day, L Deal, C Deorari, A Dilmen, U English, M Engmann, C Esamai, F Fall, C Ferriero, D Gisore, P Hazir, T Higgins, R Homer, C Hoque, D Irgens, L Islam, M de Graft-Johnson, J Joshua, M Keenan, W Khatoon, S Kieler, H Kramer, M Lackritz, E Lavender, T Lawintono, L Luhanga, R Marsh, D McMillan, D McNamara, P Mol, B Molyneux, E Mukasa, G Mutabazi, M Nacul, L Nakakeeto, M Narayanan, I Olusanya, B Osrin, D Paul, V Poets, C Reddy, U Santosham, M Sayed, R Schlabritz-Loutsevitch, N Singhal, N Smith, M Smith, P Soofi, S Spong, C Sultana, S Tshefu, A van Bel, F Gray, L Waiswa, P Wang, W Williams, S Wright, L Zaidi, A Zhang, Y Zhong, N Zuniga, I Bahl, R |
| author_facet | Yoshida, S Martines, J Lawn, J Wall, S Souza, J Rudan, I Cousens, S Aaby, P Adam, I Adhikari, R Ambalavanan, N Arifeen, S Aryal, D Asiruddin, S Baqui, A Barros, A Benn, C Bhandari, V Bhatnagar, S Bhattacharya, S Bhutta, Z Black, R Blencowe, H Bose, C Brown, J Bührer, C Carlo, W Cecatti, J Cheung, P Clark, R Colbourn, T Conde-Agudelo, A Corbett, E Czeizel, A Das, A Day, L Deal, C Deorari, A Dilmen, U English, M Engmann, C Esamai, F Fall, C Ferriero, D Gisore, P Hazir, T Higgins, R Homer, C Hoque, D Irgens, L Islam, M de Graft-Johnson, J Joshua, M Keenan, W Khatoon, S Kieler, H Kramer, M Lackritz, E Lavender, T Lawintono, L Luhanga, R Marsh, D McMillan, D McNamara, P Mol, B Molyneux, E Mukasa, G Mutabazi, M Nacul, L Nakakeeto, M Narayanan, I Olusanya, B Osrin, D Paul, V Poets, C Reddy, U Santosham, M Sayed, R Schlabritz-Loutsevitch, N Singhal, N Smith, M Smith, P Soofi, S Spong, C Sultana, S Tshefu, A van Bel, F Gray, L Waiswa, P Wang, W Williams, S Wright, L Zaidi, A Zhang, Y Zhong, N Zuniga, I Bahl, R |
| author_sort | Yoshida, S |
| collection | OXFORD |
| description | In 2013, an estimated 2.8 million newborns died and 2.7 million were stillborn. A much greater number suffer from long term impairment associated with preterm birth, intrauterine growth restriction, congenital anomalies, and perinatal or infectious causes. With the approaching deadline for the achievement of the Millennium Development Goals (MDGs) in 2015, there was a need to set the new research priorities on newborns and stillbirth with a focus not only on survival but also on health, growth and development. We therefore carried out a systematic exercise to set newborn health research priorities for 2013-2025.We used adapted Child Health and Nutrition Research Initiative (CHNRI) methods for this prioritization exercise. We identified and approached the 200 most productive researchers and 400 program experts, and 132 of them submitted research questions online. These were collated into a set of 205 research questions, sent for scoring to the 600 identified experts, and were assessed and scored by 91 experts.Nine out of top ten identified priorities were in the domain of research on improving delivery of known interventions, with simplified neonatal resuscitation program and clinical algorithms and improved skills of community health workers leading the list. The top 10 priorities in the domain of development were led by ideas on improved Kangaroo Mother Care at community level, how to improve the accuracy of diagnosis by community health workers, and perinatal audits. The 10 leading priorities for discovery research focused on stable surfactant with novel modes of administration for preterm babies, ability to diagnose fetal distress and novel tocolytic agents to delay or stop preterm labour.These findings will assist both donors and researchers in supporting and conducting research to close the knowledge gaps for reducing neonatal mortality, morbidity and long term impairment. WHO, SNL and other partners will work to generate interest among key national stakeholders, governments, NGOs, and research institutes in these priorities, while encouraging research funders to support them. We will track research funding, relevant requests for proposals and trial registers to monitor if the priorities identified by this exercise are being addressed. |
| first_indexed | 2024-03-06T19:41:22Z |
| format | Journal article |
| id | oxford-uuid:20c788b9-ecf4-4414-923a-c4c53e0441ce |
| institution | University of Oxford |
| language | English |
| last_indexed | 2024-03-06T19:41:22Z |
| publishDate | 2016 |
| publisher | Edinburgh University Global Health Society |
| record_format | dspace |
| spelling | oxford-uuid:20c788b9-ecf4-4414-923a-c4c53e0441ce2022-03-26T11:29:40ZSetting research priorities to improve global newborn health and prevent stillbirths by 2025.Journal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:20c788b9-ecf4-4414-923a-c4c53e0441ceEnglishSymplectic Elements at OxfordEdinburgh University Global Health Society2016Yoshida, SMartines, JLawn, JWall, SSouza, JRudan, ICousens, SAaby, PAdam, IAdhikari, RAmbalavanan, NArifeen, SAryal, DAsiruddin, SBaqui, ABarros, ABenn, CBhandari, VBhatnagar, SBhattacharya, SBhutta, ZBlack, RBlencowe, HBose, CBrown, JBührer, CCarlo, WCecatti, JCheung, PClark, RColbourn, TConde-Agudelo, ACorbett, ECzeizel, ADas, ADay, LDeal, CDeorari, ADilmen, UEnglish, MEngmann, CEsamai, FFall, CFerriero, DGisore, PHazir, THiggins, RHomer, CHoque, DIrgens, LIslam, Mde Graft-Johnson, JJoshua, MKeenan, WKhatoon, SKieler, HKramer, MLackritz, ELavender, TLawintono, LLuhanga, RMarsh, DMcMillan, DMcNamara, PMol, BMolyneux, EMukasa, GMutabazi, MNacul, LNakakeeto, MNarayanan, IOlusanya, BOsrin, DPaul, VPoets, CReddy, USantosham, MSayed, RSchlabritz-Loutsevitch, NSinghal, NSmith, MSmith, PSoofi, SSpong, CSultana, STshefu, Avan Bel, FGray, LWaiswa, PWang, WWilliams, SWright, LZaidi, AZhang, YZhong, NZuniga, IBahl, RIn 2013, an estimated 2.8 million newborns died and 2.7 million were stillborn. A much greater number suffer from long term impairment associated with preterm birth, intrauterine growth restriction, congenital anomalies, and perinatal or infectious causes. With the approaching deadline for the achievement of the Millennium Development Goals (MDGs) in 2015, there was a need to set the new research priorities on newborns and stillbirth with a focus not only on survival but also on health, growth and development. We therefore carried out a systematic exercise to set newborn health research priorities for 2013-2025.We used adapted Child Health and Nutrition Research Initiative (CHNRI) methods for this prioritization exercise. We identified and approached the 200 most productive researchers and 400 program experts, and 132 of them submitted research questions online. These were collated into a set of 205 research questions, sent for scoring to the 600 identified experts, and were assessed and scored by 91 experts.Nine out of top ten identified priorities were in the domain of research on improving delivery of known interventions, with simplified neonatal resuscitation program and clinical algorithms and improved skills of community health workers leading the list. The top 10 priorities in the domain of development were led by ideas on improved Kangaroo Mother Care at community level, how to improve the accuracy of diagnosis by community health workers, and perinatal audits. The 10 leading priorities for discovery research focused on stable surfactant with novel modes of administration for preterm babies, ability to diagnose fetal distress and novel tocolytic agents to delay or stop preterm labour.These findings will assist both donors and researchers in supporting and conducting research to close the knowledge gaps for reducing neonatal mortality, morbidity and long term impairment. WHO, SNL and other partners will work to generate interest among key national stakeholders, governments, NGOs, and research institutes in these priorities, while encouraging research funders to support them. We will track research funding, relevant requests for proposals and trial registers to monitor if the priorities identified by this exercise are being addressed. |
| spellingShingle | Yoshida, S Martines, J Lawn, J Wall, S Souza, J Rudan, I Cousens, S Aaby, P Adam, I Adhikari, R Ambalavanan, N Arifeen, S Aryal, D Asiruddin, S Baqui, A Barros, A Benn, C Bhandari, V Bhatnagar, S Bhattacharya, S Bhutta, Z Black, R Blencowe, H Bose, C Brown, J Bührer, C Carlo, W Cecatti, J Cheung, P Clark, R Colbourn, T Conde-Agudelo, A Corbett, E Czeizel, A Das, A Day, L Deal, C Deorari, A Dilmen, U English, M Engmann, C Esamai, F Fall, C Ferriero, D Gisore, P Hazir, T Higgins, R Homer, C Hoque, D Irgens, L Islam, M de Graft-Johnson, J Joshua, M Keenan, W Khatoon, S Kieler, H Kramer, M Lackritz, E Lavender, T Lawintono, L Luhanga, R Marsh, D McMillan, D McNamara, P Mol, B Molyneux, E Mukasa, G Mutabazi, M Nacul, L Nakakeeto, M Narayanan, I Olusanya, B Osrin, D Paul, V Poets, C Reddy, U Santosham, M Sayed, R Schlabritz-Loutsevitch, N Singhal, N Smith, M Smith, P Soofi, S Spong, C Sultana, S Tshefu, A van Bel, F Gray, L Waiswa, P Wang, W Williams, S Wright, L Zaidi, A Zhang, Y Zhong, N Zuniga, I Bahl, R Setting research priorities to improve global newborn health and prevent stillbirths by 2025. |
| title | Setting research priorities to improve global newborn health and prevent stillbirths by 2025. |
| title_full | Setting research priorities to improve global newborn health and prevent stillbirths by 2025. |
| title_fullStr | Setting research priorities to improve global newborn health and prevent stillbirths by 2025. |
| title_full_unstemmed | Setting research priorities to improve global newborn health and prevent stillbirths by 2025. |
| title_short | Setting research priorities to improve global newborn health and prevent stillbirths by 2025. |
| title_sort | setting research priorities to improve global newborn health and prevent stillbirths by 2025 |
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