Functional regulatory T cells produced by inhibiting cyclic nucleotide phosphodiesterase type 3 prevent allograft rejection.

Functional regulatory T cells produced by inhibiting cyclic nucleotide phosphodiesterase type 3 prevent allograft rejection.

Regulatory T cells (T(regs)) manipulated ex vivo have potential as cellular therapeutics in autoimmunity and transplantation. Although it is possible to expand naturally occurring T(regs), an attractive alternative possibility, particularly suited to solid organ and bone marrow transplantation, is t...

書誌詳細
主要な著者:	Feng, G, Nadig, SN, Bäckdahl, L, Beck, S, Francis, R, Schiopu, A, Whatcott, A, Wood, K, Bushell, A
フォーマット:	Journal article
言語:	English
出版事項:	2011

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