Invasive pneumococcal disease in England and Wales: vaccination implications.
Knowledge of the epidemiology of invasive pneumococcal disease (IPD) will aid in planning the use of pneumococcal vaccines. A United Kingdom (UK)-based surveillance in England and Wales (1995-1997) of 11,528 individuals with IPD and a local enhanced surveillance in the Oxford (UK) area (1995-1999) h...
| Main Authors: | , , , , , , , , , , |
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| Format: | Journal article |
| Language: | English |
| Published: |
2001
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| _version_ | 1826262803406651392 |
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| author | Sleeman, K Knox, K George, R Miller, E Waight, P Griffiths, D Efstratiou, A Broughton, K Mayon-White, R Moxon, E Crook, D |
| author_facet | Sleeman, K Knox, K George, R Miller, E Waight, P Griffiths, D Efstratiou, A Broughton, K Mayon-White, R Moxon, E Crook, D |
| author_sort | Sleeman, K |
| collection | OXFORD |
| description | Knowledge of the epidemiology of invasive pneumococcal disease (IPD) will aid in planning the use of pneumococcal vaccines. A United Kingdom (UK)-based surveillance in England and Wales (1995-1997) of 11,528 individuals with IPD and a local enhanced surveillance in the Oxford (UK) area (1995-1999) have been analyzed. IPD has a high attack rate in children, with 37.1-48.1 cases per 100,000 infants <1 year old per year, and in older persons, with 21.2-36.2 cases per 100,000 persons >65 years old per year, for England, Wales, and Oxford. The 7-valent conjugate vaccine includes serotypes causing < or =79% of IPD in children <5 years old, but only 66% in adults >65 years old. The data also indicate that IPD varies by serotype, age, and country, emphasizing that the epidemiology of IPD is heterogeneous and requires continued surveillance. |
| first_indexed | 2024-03-06T19:41:51Z |
| format | Journal article |
| id | oxford-uuid:20f644c7-e2ec-4ef3-b233-5fde1631e0e9 |
| institution | University of Oxford |
| language | English |
| last_indexed | 2024-03-06T19:41:51Z |
| publishDate | 2001 |
| record_format | dspace |
| spelling | oxford-uuid:20f644c7-e2ec-4ef3-b233-5fde1631e0e92022-03-26T11:30:28ZInvasive pneumococcal disease in England and Wales: vaccination implications.Journal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:20f644c7-e2ec-4ef3-b233-5fde1631e0e9EnglishSymplectic Elements at Oxford2001Sleeman, KKnox, KGeorge, RMiller, EWaight, PGriffiths, DEfstratiou, ABroughton, KMayon-White, RMoxon, ECrook, DKnowledge of the epidemiology of invasive pneumococcal disease (IPD) will aid in planning the use of pneumococcal vaccines. A United Kingdom (UK)-based surveillance in England and Wales (1995-1997) of 11,528 individuals with IPD and a local enhanced surveillance in the Oxford (UK) area (1995-1999) have been analyzed. IPD has a high attack rate in children, with 37.1-48.1 cases per 100,000 infants <1 year old per year, and in older persons, with 21.2-36.2 cases per 100,000 persons >65 years old per year, for England, Wales, and Oxford. The 7-valent conjugate vaccine includes serotypes causing < or =79% of IPD in children <5 years old, but only 66% in adults >65 years old. The data also indicate that IPD varies by serotype, age, and country, emphasizing that the epidemiology of IPD is heterogeneous and requires continued surveillance. |
| spellingShingle | Sleeman, K Knox, K George, R Miller, E Waight, P Griffiths, D Efstratiou, A Broughton, K Mayon-White, R Moxon, E Crook, D Invasive pneumococcal disease in England and Wales: vaccination implications. |
| title | Invasive pneumococcal disease in England and Wales: vaccination implications. |
| title_full | Invasive pneumococcal disease in England and Wales: vaccination implications. |
| title_fullStr | Invasive pneumococcal disease in England and Wales: vaccination implications. |
| title_full_unstemmed | Invasive pneumococcal disease in England and Wales: vaccination implications. |
| title_short | Invasive pneumococcal disease in England and Wales: vaccination implications. |
| title_sort | invasive pneumococcal disease in england and wales vaccination implications |
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