Cancer stem cell radioresistance and enrichment: where frontline radiation therapy may fail in lung and esophageal cancers

Many studies have highlighted the role cancer stem cells (CSC) play in the development and progression of various types of cancer including lung and esophageal cancer. More recently, it has been proposed that the presence of CSCs affects treatment efficacy and patient prognosis. In reviewing this ne...

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Main Authors: Nguyen, G, Murph, M, Chang, J
Format: Journal article
Language:English
Published: Multidisciplinary Digital Publishing Institute 2011
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author Nguyen, G
Murph, M
Chang, J
author_facet Nguyen, G
Murph, M
Chang, J
author_sort Nguyen, G
collection OXFORD
description Many studies have highlighted the role cancer stem cells (CSC) play in the development and progression of various types of cancer including lung and esophageal cancer. More recently, it has been proposed that the presence of CSCs affects treatment efficacy and patient prognosis. In reviewing this new area of cancer biology, we will give an overview of the current literature regarding lung and esophageal CSCs and radioresistance of CSC, and discuss the potential therapeutic applications of these findings.
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spelling oxford-uuid:211ccb2d-a32c-40dd-9849-e9fd838328912022-03-26T11:31:26ZCancer stem cell radioresistance and enrichment: where frontline radiation therapy may fail in lung and esophageal cancersJournal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:211ccb2d-a32c-40dd-9849-e9fd83832891EnglishOxford University Research Archive - ValetMultidisciplinary Digital Publishing Institute2011Nguyen, GMurph, MChang, JMany studies have highlighted the role cancer stem cells (CSC) play in the development and progression of various types of cancer including lung and esophageal cancer. More recently, it has been proposed that the presence of CSCs affects treatment efficacy and patient prognosis. In reviewing this new area of cancer biology, we will give an overview of the current literature regarding lung and esophageal CSCs and radioresistance of CSC, and discuss the potential therapeutic applications of these findings.
spellingShingle Nguyen, G
Murph, M
Chang, J
Cancer stem cell radioresistance and enrichment: where frontline radiation therapy may fail in lung and esophageal cancers
title Cancer stem cell radioresistance and enrichment: where frontline radiation therapy may fail in lung and esophageal cancers
title_full Cancer stem cell radioresistance and enrichment: where frontline radiation therapy may fail in lung and esophageal cancers
title_fullStr Cancer stem cell radioresistance and enrichment: where frontline radiation therapy may fail in lung and esophageal cancers
title_full_unstemmed Cancer stem cell radioresistance and enrichment: where frontline radiation therapy may fail in lung and esophageal cancers
title_short Cancer stem cell radioresistance and enrichment: where frontline radiation therapy may fail in lung and esophageal cancers
title_sort cancer stem cell radioresistance and enrichment where frontline radiation therapy may fail in lung and esophageal cancers
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AT murphm cancerstemcellradioresistanceandenrichmentwherefrontlineradiationtherapymayfailinlungandesophagealcancers
AT changj cancerstemcellradioresistanceandenrichmentwherefrontlineradiationtherapymayfailinlungandesophagealcancers