Cancer stem cell radioresistance and enrichment: where frontline radiation therapy may fail in lung and esophageal cancers
Many studies have highlighted the role cancer stem cells (CSC) play in the development and progression of various types of cancer including lung and esophageal cancer. More recently, it has been proposed that the presence of CSCs affects treatment efficacy and patient prognosis. In reviewing this ne...
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Format: | Journal article |
Language: | English |
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Multidisciplinary Digital Publishing Institute
2011
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_version_ | 1797057857617657856 |
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author | Nguyen, G Murph, M Chang, J |
author_facet | Nguyen, G Murph, M Chang, J |
author_sort | Nguyen, G |
collection | OXFORD |
description | Many studies have highlighted the role cancer stem cells (CSC) play in the development and progression of various types of cancer including lung and esophageal cancer. More recently, it has been proposed that the presence of CSCs affects treatment efficacy and patient prognosis. In reviewing this new area of cancer biology, we will give an overview of the current literature regarding lung and esophageal CSCs and radioresistance of CSC, and discuss the potential therapeutic applications of these findings. |
first_indexed | 2024-03-06T19:42:21Z |
format | Journal article |
id | oxford-uuid:211ccb2d-a32c-40dd-9849-e9fd83832891 |
institution | University of Oxford |
language | English |
last_indexed | 2024-03-06T19:42:21Z |
publishDate | 2011 |
publisher | Multidisciplinary Digital Publishing Institute |
record_format | dspace |
spelling | oxford-uuid:211ccb2d-a32c-40dd-9849-e9fd838328912022-03-26T11:31:26ZCancer stem cell radioresistance and enrichment: where frontline radiation therapy may fail in lung and esophageal cancersJournal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:211ccb2d-a32c-40dd-9849-e9fd83832891EnglishOxford University Research Archive - ValetMultidisciplinary Digital Publishing Institute2011Nguyen, GMurph, MChang, JMany studies have highlighted the role cancer stem cells (CSC) play in the development and progression of various types of cancer including lung and esophageal cancer. More recently, it has been proposed that the presence of CSCs affects treatment efficacy and patient prognosis. In reviewing this new area of cancer biology, we will give an overview of the current literature regarding lung and esophageal CSCs and radioresistance of CSC, and discuss the potential therapeutic applications of these findings. |
spellingShingle | Nguyen, G Murph, M Chang, J Cancer stem cell radioresistance and enrichment: where frontline radiation therapy may fail in lung and esophageal cancers |
title | Cancer stem cell radioresistance and enrichment: where frontline radiation therapy may fail in lung and esophageal cancers |
title_full | Cancer stem cell radioresistance and enrichment: where frontline radiation therapy may fail in lung and esophageal cancers |
title_fullStr | Cancer stem cell radioresistance and enrichment: where frontline radiation therapy may fail in lung and esophageal cancers |
title_full_unstemmed | Cancer stem cell radioresistance and enrichment: where frontline radiation therapy may fail in lung and esophageal cancers |
title_short | Cancer stem cell radioresistance and enrichment: where frontline radiation therapy may fail in lung and esophageal cancers |
title_sort | cancer stem cell radioresistance and enrichment where frontline radiation therapy may fail in lung and esophageal cancers |
work_keys_str_mv | AT nguyeng cancerstemcellradioresistanceandenrichmentwherefrontlineradiationtherapymayfailinlungandesophagealcancers AT murphm cancerstemcellradioresistanceandenrichmentwherefrontlineradiationtherapymayfailinlungandesophagealcancers AT changj cancerstemcellradioresistanceandenrichmentwherefrontlineradiationtherapymayfailinlungandesophagealcancers |