Bifunctional iminophosphorane-catalyzed enantioselective sulfa-michael addition to unactivated α,β-unsaturated amides
The first metal-free catalytic intermolecular enantioselective Michael addition to unactivated α,β-unsaturated amides is described. Consistently high enantiomeric excesses and yields were obtained over a wide range of alkyl thiol pronucleophiles and electrophiles under mild reaction conditions, enab...
| Main Authors: | , , , , |
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| Format: | Journal article |
| Jezik: | English |
| Izdano: |
American Chemical Society
2022
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