Bifunctional iminophosphorane-catalyzed enantioselective sulfa-michael addition to unactivated α,β-unsaturated amides

The first metal-free catalytic intermolecular enantioselective Michael addition to unactivated α,β-unsaturated amides is described. Consistently high enantiomeric excesses and yields were obtained over a wide range of alkyl thiol pronucleophiles and electrophiles under mild reaction conditions, enab...

Disgrifiad llawn

Manylion Llyfryddiaeth
Prif Awduron: Rozsar, D, Formica, M, Yamazaki, K, Hamlin, TA, Dixon, DJ
Fformat: Journal article
Iaith:English
Cyhoeddwyd: American Chemical Society 2022