Bifunctional iminophosphorane-catalyzed enantioselective sulfa-michael addition to unactivated α,β-unsaturated amides

The first metal-free catalytic intermolecular enantioselective Michael addition to unactivated α,β-unsaturated amides is described. Consistently high enantiomeric excesses and yields were obtained over a wide range of alkyl thiol pronucleophiles and electrophiles under mild reaction conditions, enab...

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Những tác giả chính: Rozsar, D, Formica, M, Yamazaki, K, Hamlin, TA, Dixon, DJ
Định dạng: Journal article
Ngôn ngữ:English
Được phát hành: American Chemical Society 2022