Investigation of a transgenic mouse model of familial dilated cardiomyopathy.

We have investigated a transgenic mouse model of inherited dilated cardiomyopathy that stably expresses the ACTC E361G mutation at around 50% of total actin in the heart. F-actin isolated from ACTC E361G mouse hearts was incorporated into thin filaments with native human tropomyosin and troponin and...

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Những tác giả chính: Song, W, Dyer, E, Stuckey, D, Leung, M, Memo, M, Mansfield, C, Ferenczi, M, Liu, K, Redwood, C, Nowak, K, Harding, S, Clarke, K, Wells, D, Marston, S
Định dạng: Journal article
Ngôn ngữ:English
Được phát hành: 2010