Hypoxia- and Postirradiation reoxygenation-induced HMHA1/ARHGAP45 expression contributes to cancer cell invasion in a HIF-dependent manner

Background: Cancer cells in severely hypoxic regions have been reported to invade towards tumour blood vessels after surviving radiotherapy in a postirradiation reoxygenation- and hypoxia-inducible factor (HIF)-dependent manner and cause recurrence. However, how HIF induces invasiveness of irradiate...

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Bibliographic Details
Main Authors: Lee, PWT, Suwa, T, Kobayashi, M, Yang, H, Koseki, LR, Takeuchi, S, Chow, CCT, Yasuhara, T, Harada, H
Format: Journal article
Language:English
Published: Springer Nature [academic journals on nature.com] 2024