The promiscuous MLL gene links chromosomal translocations to cellular differentiation and tumour tropism.
MLL is a promiscuous gene involved in a diversity of chromosomal fusions in haematological malignancies, usually resulting from chromosomal translocations. MLL-associated chromosomal rearrangements usually occur in tumours of specific haematological lineages, suggesting a crucial role for the MLL fu...
Main Authors: | Collins, E, Rabbitts, T |
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Format: | Journal article |
Language: | English |
Published: |
2002
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