The promiscuous MLL gene links chromosomal translocations to cellular differentiation and tumour tropism.

MLL is a promiscuous gene involved in a diversity of chromosomal fusions in haematological malignancies, usually resulting from chromosomal translocations. MLL-associated chromosomal rearrangements usually occur in tumours of specific haematological lineages, suggesting a crucial role for the MLL fu...

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Bibliographic Details
Main Authors: Collins, E, Rabbitts, T
Format: Journal article
Language:English
Published: 2002

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