2-Oxoglutarate analogue inhibitors of prolyl hydroxylase domain 2.

Analogues of the 2-oxoglutarate cosubstrate of the human oxygen sensing enzyme prolyl hydroxylase domain 2 (PHD2) with variations in the potential iron-chelating group were screened as inhibitors and for binding (using non-denaturing electrospray ionization mass spectrometry) to PHD2.

書誌詳細
主要な著者: Mecinović, J, Loenarz, C, Chowdhury, R, Schofield, C
フォーマット: Journal article
言語:English
出版事項: 2009