Tumor necrosis factor receptor p55 mediates deletion of peripheral cytotoxic T lymphocytes in vivo.

Tumor necrosis factor receptor p55 mediates deletion of peripheral cytotoxic T lymphocytes in vivo.

Cellular death of activated lymphocytes down-regulates immune responses and is involved in maintaining self tolerance. Signals associated with ligation of the membrane molecule Fas lead to lymphocyte apoptosis, but additional, Fas-independent mechanisms have been postulated. Here, we show a marked e...

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Bibliographic Details
Main Authors:	Speiser, D, Sebzda, E, Ohteki, T, Bachmann, M, Pfeffer, K, Mak, T, Ohashi, P
Format:	Journal article
Language:	English
Published:	1996

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