Genetic and epigenetic basis of clonal advantage during the evolution of acute myeloid leukaemia
<p>Acute myeloid leukaemia (AML) is an aggressive malignant disorder of immature myeloid cells in the bone marrow. The outcome of older AML patients who are unfit for intensive chemotherapy remains dismal. Relapse, which is the main cause of mortality, occurs due to Darwinian clonal selection...
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| Format: | Thesis |
| Language: | English |
| Published: |
2024
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