Fyn and ZAP-70 are required for Vav phosphorylation in T cells stimulated by antigen-presenting cells.
In T cells, triggering of the T cell antigen receptor or of the co-stimulatory receptor CD28 can direct tyrosine phosphorylation of the signaling protein Vav. We investigated the role played by the protein tyrosine kinases Fyn, Lck, and ZAP-70 in these processes in a T cell hybridoma after physiolog...
Prif Awduron: | , , , |
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Fformat: | Journal article |
Iaith: | English |
Cyhoeddwyd: |
1998
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