Antibody inhibition of synaptosomal protein of 25 kDa (SNAP-25) and syntaxin 1 reduces rapid exocytosis in insulin-secreting cells.
SNARE-proteins (soluble NSF-attachment protein receptor) are important for Ca(2+)-dependent exocytosis. We have used capacitance measurements and confocal imaging to dissect the role of synaptosomal protein of 25 kDa (SNAP-25) and syntaxin 1 in rapid exocytosis in insulin-secreting pancreatic beta-c...
Main Authors: | Vikman, J, Ma, X, Hockerman, G, Rorsman, P, Eliasson, L |
---|---|
Format: | Journal article |
Language: | English |
Published: |
2006
|
Similar Items
-
A novel function for SNAP29 (synaptosomal-associated protein of 29 kDa) in mast cell phagocytosis.
by: Jordan Wesolowski, et al.
Published: (2012-01-01) -
α-SNAP prevents docking of the acrosome during sperm exocytosis because it sequesters monomeric syntaxin.
by: Facundo Rodríguez, et al.
Published: (2011-01-01) -
The mesoscale organization of syntaxin 1A and SNAP25 is determined by SNARE–SNARE interactions
by: Jasmin Mertins, et al.
Published: (2021-11-01) -
Mining the potential prognostic value of synaptosomal-associated protein 25 (SNAP25) in colon cancer based on stromal-immune score
by: Jinyan Zou, et al.
Published: (2020-10-01) -
Regulated exocytosis of single insulin granules and synaptic-like vesicles in membrane patches of insulin secreting cells
by: Macdonald, P, et al.
Published: (2004)