Placental disease and the maternal syndrome of preeclampsia: missing links?
Preeclampsia remains a significant obstetric risk worldwide. The pathophysiology of preeclampsia is complex, with multiple stages involving maladaptations in both placental and maternal physiology. The placenta links the pre-clinical stage of impaired remodeling of the uterine vasculature, occurring...
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Format: | Journal article |
Language: | English |
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2013
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author | Tannetta, D Sargent, I |
author_facet | Tannetta, D Sargent, I |
author_sort | Tannetta, D |
collection | OXFORD |
description | Preeclampsia remains a significant obstetric risk worldwide. The pathophysiology of preeclampsia is complex, with multiple stages involving maladaptations in both placental and maternal physiology. The placenta links the pre-clinical stage of impaired remodeling of the uterine vasculature, occurring in early pregnancy, to the later clinical stages characterised by the maternal syndrome of hypertension and proteinuria. This review focuses on some of the recent candidates for the missing links in this process. |
first_indexed | 2024-03-06T19:43:33Z |
format | Journal article |
id | oxford-uuid:217b285a-eea4-4a7a-8157-1ac31220f1ae |
institution | University of Oxford |
language | English |
last_indexed | 2024-03-06T19:43:33Z |
publishDate | 2013 |
record_format | dspace |
spelling | oxford-uuid:217b285a-eea4-4a7a-8157-1ac31220f1ae2022-03-26T11:33:41ZPlacental disease and the maternal syndrome of preeclampsia: missing links?Journal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:217b285a-eea4-4a7a-8157-1ac31220f1aeEnglishSymplectic Elements at Oxford2013Tannetta, DSargent, IPreeclampsia remains a significant obstetric risk worldwide. The pathophysiology of preeclampsia is complex, with multiple stages involving maladaptations in both placental and maternal physiology. The placenta links the pre-clinical stage of impaired remodeling of the uterine vasculature, occurring in early pregnancy, to the later clinical stages characterised by the maternal syndrome of hypertension and proteinuria. This review focuses on some of the recent candidates for the missing links in this process. |
spellingShingle | Tannetta, D Sargent, I Placental disease and the maternal syndrome of preeclampsia: missing links? |
title | Placental disease and the maternal syndrome of preeclampsia: missing links? |
title_full | Placental disease and the maternal syndrome of preeclampsia: missing links? |
title_fullStr | Placental disease and the maternal syndrome of preeclampsia: missing links? |
title_full_unstemmed | Placental disease and the maternal syndrome of preeclampsia: missing links? |
title_short | Placental disease and the maternal syndrome of preeclampsia: missing links? |
title_sort | placental disease and the maternal syndrome of preeclampsia missing links |
work_keys_str_mv | AT tannettad placentaldiseaseandthematernalsyndromeofpreeclampsiamissinglinks AT sargenti placentaldiseaseandthematernalsyndromeofpreeclampsiamissinglinks |