Retinoic acid signaling in thymic epithelial cells regulates thymopoiesis
Despite the essential role of thymic epithelial cells (TEC) in T cell development, the signals regulating TEC differentiation and homeostasis remain incompletely understood. In this study, we show a key in vivo role for the vitamin A metabolite, retinoic acid (RA), in TEC homeostasis. In the absence...
Hlavní autoři: | Wendland, K, Niss, K, Kotarsky, K, Wu, N, White, A, Jendholm, J, Rivollier, A, Izarzugaza, J, Brunak, S, Holländer, G, Anderson, G, Sitnik, K, Agace, W |
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Médium: | Journal article |
Jazyk: | English |
Vydáno: |
American Association of Immunologists
2018
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