Reduction of C X to CH2
The complete reduction of the carbonyl group of an aldehyde or ketone to a methylene/methyl group is generally achieved using the well-known Wolff-Kishner and Clemmensen reductions and these two transformations form the majority of the chapter. A range of useful procedures along with possible side r...
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| Format: | Book section |
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Elsevier
2014
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| _version_ | 1797057958308216832 |
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| author | Burton, J |
| author_facet | Burton, J |
| author_sort | Burton, J |
| collection | OXFORD |
| description | The complete reduction of the carbonyl group of an aldehyde or ketone to a methylene/methyl group is generally achieved using the well-known Wolff-Kishner and Clemmensen reductions and these two transformations form the majority of the chapter. A range of useful procedures along with possible side reactions is presented; examples will be mainly taken from the recent literature. The use of ionic hydrogenation and metal-catalyzed hydrogenolysis, using predominantly aromatic ketones and aldehydes, is also presented. Other methods are briefly discussed. © 2014 Elsevier Ltd. All rights reserved. |
| first_indexed | 2024-03-06T19:43:46Z |
| format | Book section |
| id | oxford-uuid:218d3caf-ac88-4f96-8820-f51371fe68b3 |
| institution | University of Oxford |
| last_indexed | 2024-03-06T19:43:46Z |
| publishDate | 2014 |
| publisher | Elsevier |
| record_format | dspace |
| spelling | oxford-uuid:218d3caf-ac88-4f96-8820-f51371fe68b32022-03-26T11:34:07ZReduction of C X to CH2 Book sectionhttp://purl.org/coar/resource_type/c_3248uuid:218d3caf-ac88-4f96-8820-f51371fe68b3Symplectic Elements at OxfordElsevier2014Burton, JThe complete reduction of the carbonyl group of an aldehyde or ketone to a methylene/methyl group is generally achieved using the well-known Wolff-Kishner and Clemmensen reductions and these two transformations form the majority of the chapter. A range of useful procedures along with possible side reactions is presented; examples will be mainly taken from the recent literature. The use of ionic hydrogenation and metal-catalyzed hydrogenolysis, using predominantly aromatic ketones and aldehydes, is also presented. Other methods are briefly discussed. © 2014 Elsevier Ltd. All rights reserved. |
| spellingShingle | Burton, J Reduction of C X to CH2 |
| title | Reduction of C X to CH2
|
| title_full | Reduction of C X to CH2
|
| title_fullStr | Reduction of C X to CH2
|
| title_full_unstemmed | Reduction of C X to CH2
|
| title_short | Reduction of C X to CH2
|
| title_sort | reduction of c x to ch2 |
| work_keys_str_mv | AT burtonj reductionofcxtoch2 |