Bayesian meta‐analysis across genome‐wide association studies of diverse phenotypes

Genome‐wide association studies (GWAS) are a powerful tool for understanding the genetic basis of diseases and traits, but most studies have been conducted in isolation, with a focus on either a single or a set of closely related phenotypes. We describe MetABF, a simple Bayesian framework for perfor...

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Hlavní autoři: Trochet, H, Pirinen, M, Band, G, Jostins, L, McVean, G, Spencer, C
Médium: Journal article
Jazyk:English
Vydáno: Wiley 2019