Lactate dehydrogenase-B is silenced by promoter hypermethylation in human prostate cancer.

In order to identify novel candidates associated with prostate cancer metastasis, we compared the proteomic profile of the poorly metastatic human prostate cancer cell line LNCaP, with its highly metastatic variant LNCaP-LN3, by two-dimensional gel electrophoresis. A major protein spot (pI of 5.9 an...

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Autori principali: Leiblich, A, Cross, S, Catto, J, Phillips, J, Leung, H, Hamdy, F, Rehman, I
Natura: Journal article
Lingua:English
Pubblicazione: 2006