Immune enhancement of nitroreductase-induced cytotoxicity: studies using a bicistronic adenovirus vector.
The nitroreductase (NR)/CB1954 enzyme prodrug system has given promising results in preclinical studies and is currently being assessed in phase I clinical trials. It is well established that there is an immune component to the bystander effect observed with other systems such as thymidine kinase an...
| मुख्य लेखकों: | , , , , , |
|---|---|
| स्वरूप: | Journal article |
| भाषा: | English |
| प्रकाशित: |
2003
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