Immune enhancement of nitroreductase-induced cytotoxicity: studies using a bicistronic adenovirus vector.

The nitroreductase (NR)/CB1954 enzyme prodrug system has given promising results in preclinical studies and is currently being assessed in phase I clinical trials. It is well established that there is an immune component to the bystander effect observed with other systems such as thymidine kinase an...

詳細記述

書誌詳細
主要な著者: Green, N, McNeish, I, Doshi, R, Searle, P, Kerr, D, Young, L
フォーマット: Journal article
言語:English
出版事項: 2003