Characterization of mechanisms positioning costimulatory complexes in immune synapses

Small immunoglobulin superfamily (sIGSF) adhesion complexes form a corolla of microdomains around an integrin ring and secretory core during immunological synapse (IS) formation. The corolla recruits and retains major costimulatory/checkpoint complexes, such as CD28, making forces that govern coroll...

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Bibliographic Details
Main Authors: Siokis, A, Robert, PA, Demetriou, P, Kvalvaag, A, Valvo, S, Mayya, V, Dustin, ML, Meyer-Hermann, M
Format: Journal article
Language:English
Published: Cell Press 2021