Determination of the real effect of genes identified in GWAS: The example of IL2RA in multiple sclerosis
Genome-wide association studies (GWAS), although efficient to detect genes involved in complex diseases, are not designed to measure the real effect of the genes. This is illustrated here by the example of IL2RA in multiple sclerosis (MS). Association between IL2RA and MS is clearly established, alt...
Main Authors: | Babron, M, Perdry, H, Handel, A, Ramagopalan, S, Damotte, V, Fontaine, B, Müller-Myhsok, B, Ebers, G, Clerget-Darpoux, F |
---|---|
Format: | Journal article |
Published: |
2012
|
Similar Items
-
Determination of the real effect of genes identified in GWAS: the example of IL2RA in multiple sclerosis.
by: Babron, M, et al.
Published: (2012) -
The False Dawn of Polygenic Risk Scores for Human Disease Prediction
by: Anthony F. Herzig, et al.
Published: (2022-07-01) -
New Therapeutic Strategies for Lung Cancer
by: Philippe Icard, et al.
Published: (2021-04-01) -
Environmental factors and their timing in adult-onset multiple sclerosis
by: Handel, A, et al.
Published: (2010) -
Environmental factors and their timing in adult-onset multiple sclerosis.
by: Handel, A, et al.
Published: (2010)