Asymmetric synthesis of (2S,3S)- and (2R,3S)-2,3-diaminobutanoic acids, non-protein amino-acid diastereomers found in a number of peptide antibiotics
(2S,3S)- and (2R,3S)-2,3-diaminobutanoic acids (DABA) are uncommon, naturally occurring amino acid diastereomers found as components of a number of peptide antibiotics. These 2,3-diamino acids have been synthesised by direct and indirect routes, with addition of a chiral lithium amide to tert-butyl...
| Autores principales: | , , |
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| Formato: | Journal article |
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1996
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| _version_ | 1826263028289503232 |
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| author | Burke, A Davies, S Hedgecock, C |
| author_facet | Burke, A Davies, S Hedgecock, C |
| author_sort | Burke, A |
| collection | OXFORD |
| description | (2S,3S)- and (2R,3S)-2,3-diaminobutanoic acids (DABA) are uncommon, naturally occurring amino acid diastereomers found as components of a number of peptide antibiotics. These 2,3-diamino acids have been synthesised by direct and indirect routes, with addition of a chiral lithium amide to tert-butyl crotonate as a key step. |
| first_indexed | 2024-03-06T19:45:11Z |
| format | Journal article |
| id | oxford-uuid:220d7bc9-28ee-4273-a588-397ecc39cc21 |
| institution | University of Oxford |
| last_indexed | 2024-03-06T19:45:11Z |
| publishDate | 1996 |
| record_format | dspace |
| spelling | oxford-uuid:220d7bc9-28ee-4273-a588-397ecc39cc212022-03-26T11:36:35ZAsymmetric synthesis of (2S,3S)- and (2R,3S)-2,3-diaminobutanoic acids, non-protein amino-acid diastereomers found in a number of peptide antibioticsJournal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:220d7bc9-28ee-4273-a588-397ecc39cc21Symplectic Elements at Oxford1996Burke, ADavies, SHedgecock, C(2S,3S)- and (2R,3S)-2,3-diaminobutanoic acids (DABA) are uncommon, naturally occurring amino acid diastereomers found as components of a number of peptide antibiotics. These 2,3-diamino acids have been synthesised by direct and indirect routes, with addition of a chiral lithium amide to tert-butyl crotonate as a key step. |
| spellingShingle | Burke, A Davies, S Hedgecock, C Asymmetric synthesis of (2S,3S)- and (2R,3S)-2,3-diaminobutanoic acids, non-protein amino-acid diastereomers found in a number of peptide antibiotics |
| title | Asymmetric synthesis of (2S,3S)- and (2R,3S)-2,3-diaminobutanoic acids, non-protein amino-acid diastereomers found in a number of peptide antibiotics |
| title_full | Asymmetric synthesis of (2S,3S)- and (2R,3S)-2,3-diaminobutanoic acids, non-protein amino-acid diastereomers found in a number of peptide antibiotics |
| title_fullStr | Asymmetric synthesis of (2S,3S)- and (2R,3S)-2,3-diaminobutanoic acids, non-protein amino-acid diastereomers found in a number of peptide antibiotics |
| title_full_unstemmed | Asymmetric synthesis of (2S,3S)- and (2R,3S)-2,3-diaminobutanoic acids, non-protein amino-acid diastereomers found in a number of peptide antibiotics |
| title_short | Asymmetric synthesis of (2S,3S)- and (2R,3S)-2,3-diaminobutanoic acids, non-protein amino-acid diastereomers found in a number of peptide antibiotics |
| title_sort | asymmetric synthesis of 2s 3s and 2r 3s 2 3 diaminobutanoic acids non protein amino acid diastereomers found in a number of peptide antibiotics |
| work_keys_str_mv | AT burkea asymmetricsynthesisof2s3sand2r3s23diaminobutanoicacidsnonproteinaminoaciddiastereomersfoundinanumberofpeptideantibiotics AT daviess asymmetricsynthesisof2s3sand2r3s23diaminobutanoicacidsnonproteinaminoaciddiastereomersfoundinanumberofpeptideantibiotics AT hedgecockc asymmetricsynthesisof2s3sand2r3s23diaminobutanoicacidsnonproteinaminoaciddiastereomersfoundinanumberofpeptideantibiotics |