Drug action at the 5-HT(1A) receptor in vivo: autoreceptor and postsynaptic receptor occupancy examined with PET and [carbonyl-(11)C]WAY-100635.

Serotonin(1A) (5-HT(1A)) receptors have been implicated in the pathophysiology and treatment of anxiety and depression and are a target for novel drug development. In this qualitative study, positron emission tomography (PET) and [carbonyl-(11)C]WAY-100635 were used to assess 5-HT(1A) autoreceptor a...

Disgrifiad llawn

Manylion Llyfryddiaeth
Prif Awduron: Rabiner, E, Gunn, R, Wilkins, MR, Sargent, P, Mocaer, E, Sedman, E, Cowen, P, Grasby, P
Fformat: Journal article
Iaith:English
Cyhoeddwyd: 2000