B cell growth and differentiation induced by supernatants of transformed epithelial cell lines.
Growth and differentiation of B cells is thought to be regulated by soluble factors derived from T cells. However, human T cell lines and hybridomas have proved to be notoriously unreliable and unstable sources of such factors. We report here that three stable human bladder carcinoma cell lines T24,...
| Main Authors: | , , , , , , |
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| Format: | Journal article |
| Language: | English |
| Published: |
1986
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| _version_ | 1797058089342468096 |
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| author | Rawle, F Shields, J Smith, S Iliescu, V Merkenschlager, M Beverley, P Callard, R |
| author_facet | Rawle, F Shields, J Smith, S Iliescu, V Merkenschlager, M Beverley, P Callard, R |
| author_sort | Rawle, F |
| collection | OXFORD |
| description | Growth and differentiation of B cells is thought to be regulated by soluble factors derived from T cells. However, human T cell lines and hybridomas have proved to be notoriously unreliable and unstable sources of such factors. We report here that three stable human bladder carcinoma cell lines T24, RT4 and 5637 produce, in a constitutive fashion, factors which promote growth and differentiation of human B cells. |
| first_indexed | 2024-03-06T19:45:41Z |
| format | Journal article |
| id | oxford-uuid:2239fec7-fe0d-4017-89d6-317d59d170da |
| institution | University of Oxford |
| language | English |
| last_indexed | 2024-03-06T19:45:41Z |
| publishDate | 1986 |
| record_format | dspace |
| spelling | oxford-uuid:2239fec7-fe0d-4017-89d6-317d59d170da2022-03-26T11:37:33ZB cell growth and differentiation induced by supernatants of transformed epithelial cell lines.Journal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:2239fec7-fe0d-4017-89d6-317d59d170daEnglishSymplectic Elements at Oxford1986Rawle, FShields, JSmith, SIliescu, VMerkenschlager, MBeverley, PCallard, RGrowth and differentiation of B cells is thought to be regulated by soluble factors derived from T cells. However, human T cell lines and hybridomas have proved to be notoriously unreliable and unstable sources of such factors. We report here that three stable human bladder carcinoma cell lines T24, RT4 and 5637 produce, in a constitutive fashion, factors which promote growth and differentiation of human B cells. |
| spellingShingle | Rawle, F Shields, J Smith, S Iliescu, V Merkenschlager, M Beverley, P Callard, R B cell growth and differentiation induced by supernatants of transformed epithelial cell lines. |
| title | B cell growth and differentiation induced by supernatants of transformed epithelial cell lines. |
| title_full | B cell growth and differentiation induced by supernatants of transformed epithelial cell lines. |
| title_fullStr | B cell growth and differentiation induced by supernatants of transformed epithelial cell lines. |
| title_full_unstemmed | B cell growth and differentiation induced by supernatants of transformed epithelial cell lines. |
| title_short | B cell growth and differentiation induced by supernatants of transformed epithelial cell lines. |
| title_sort | b cell growth and differentiation induced by supernatants of transformed epithelial cell lines |
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