Nano-particle vaccination combined with TLR-7 and -9 ligands triggers memory and effector CD8⁺ T-cell responses in melanoma patients.

Nano-particle vaccination combined with TLR-7 and -9 ligands triggers memory and effector CD8⁺ T-cell responses in melanoma patients.

Optimal vaccine strategies must be identified for improving T-cell vaccination against infectious and malignant diseases. MelQbG10 is a virus-like nano-particle loaded with A-type CpG-oligonucleotides (CpG-ODN) and coupled to peptide(16-35) derived from Melan-A/MART-1. In this phase IIa clinical st...

وصف كامل

التفاصيل البيبلوغرافية
المؤلفون الرئيسيون: Goldinger, S, Dummer, R, Baumgaertner, P, Mihic-Probst, D, Schwarz, K, Hammann-Haenni, A, Willers, J, Geldhof, C, Prior, J, Kündig, T, Michielin, O, Bachmann, M, Speiser, D
التنسيق: Journal article
اللغة:English
منشور في: 2012

مواد مشابهة