Gene-gene interactions in breast cancer susceptibility

Gene-gene interactions in breast cancer susceptibility

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There have been few definitive examples of gene-gene interactions in humans. Through mutational analyses in 7325 individuals, we report four interactions (defined as departures from a multiplicative model) between mutations in the breast cancer susceptibility genes ATM and CHEK2 with BRCA1 and BRCA2...

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Main Authors: Turnbull, C, Seal, S, Renwick, A, Warren-perry, M, Hughes, D, Elliott, A, Pernet, D, Peock, S, Adlard, J, Barwell, J, Berg, J, Brady, A, Brewer, C, Brice, G, Chapman, C, Cook, J, Davidson, R, Donaldson, A, Douglas, F, Greenhalgh, L, Henderson, A, Izatt, L, Kumar, A, Lalloo, F, Miedzybrodzka, Z
Formato: Journal article
Idioma:English
Publicado: 2012

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