Measuring intracellular pH in the heart using hyperpolarized carbon dioxide and bicarbonate: a 13C and 31P magnetic resonance spectroscopy study.
AIMS: Technological limitations have restricted in vivo assessment of intracellular pH (pH(i)) in the myocardium. The aim of this study was to evaluate the potential of hyperpolarized [1-(13)C]pyruvate, coupled with (13)C magnetic resonance spectroscopy (MRS), to measure pH(i) in the healthy and dis...
Main Authors: | Schroeder, M, Swietach, P, Atherton, H, Gallagher, F, Lee, P, Radda, G, Clarke, K, Tyler, D |
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Format: | Journal article |
Language: | English |
Published: |
2010
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