RNA sequencing identifies dysregulation of the human pancreatic islet transcriptome by the saturated fatty acid palmitate.
Pancreatic β-cell dysfunction and death are central in the pathogenesis of type 2 diabetes (T2D). Saturated fatty acids cause β-cell failure and contribute to diabetes development in genetically predisposed individuals. Here we used RNA sequencing to map transcripts expressed in five palmitate-treat...
প্রধান লেখক: | Cnop, M, Abdulkarim, B, Bottu, G, Cunha, D, Igoillo-Esteve, M, Masini, M, Turatsinze, J, Griebel, T, Villate, O, Santin, I, Bugliani, M, Ladriere, L, Marselli, L, McCarthy, M, Marchetti, P, Sammeth, M, Eizirik, D |
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বিন্যাস: | Journal article |
ভাষা: | English |
প্রকাশিত: |
American Diabetes Association Inc.
2014
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অনুরূপ উপাদানগুলি
অনুরূপ উপাদানগুলি
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RNA-sequencing identifies dysregulation of the human pancreatic islet transcriptome by the saturated fatty acid palmitate
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