The role of Foxp3+ regulatory T-cells in transplant tolerance
<p>A major conceptual shift in immunology has been the recent discovery of regulatory T-cells (Treg), of which CD4+Foxp3+ cells are already known to be essential to self-tolerance. Their role in transplant tolerance remains unproven due to the absence of a natural cell surface marker by which...
| Main Authors: | , |
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| Format: | Thesis |
| Language: | English |
| Published: |
2011
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| Subjects: |