Antimalarial activity and interactions between quinine, dihydroquinine and 3-hydroxyquinine against Plasmodium falciparum in vitro.
The antimalarial activities of quinine, dihydroquinine (a natural impurity found in commercial pharmaceutical formulations of quinine) and 3-hydroxyquinine (the principal metabolite of quinine in humans) were tested both individually and in pairs against 5 strains of Plasmodium falciparum isolated f...
Main Authors: | Nontprasert, A, Pukrittayakamee, S, Kyle, D, Vanijanonta, S, White, N |
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Format: | Journal article |
Language: | English |
Published: |
1996
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