Accumulation of glucosylceramide in murine testis, caused by inhibition of beta-glucosidase 2: implications for spermatogenesis.

One of the hallmarks of male germ cell development is the formation of a specialized secretory organelle, the acrosome. This process can be pharmacologically disturbed in C57BL/6 mice, and thus infertility can be induced, by small molecular sugar-like compounds (alkylated imino sugars). Here the bio...

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Bibliografski detalji
Glavni autori: Walden, C, Sandhoff, R, Chuang, C, Yildiz, Y, Butters, T, Dwek, R, Platt, F, van der Spoel, A
Format: Journal article
Jezik:English
Izdano: 2007