Peripheral DNA methylation, cognitive decline and brain ageing: Pilot findings from the Whitehall II Imaging Study

Peripheral DNA methylation, cognitive decline and brain ageing: Pilot findings from the Whitehall II Imaging Study

<h4>Background</h4> <p>DNA methylation (DNAm) has been linked with the pathophysiology of brain aging, cognitive impairment and dementia.</p> <h4>Methods</h4> <p>The present study investigated the association between blood genome-wide DNAm profiles, cogniti...

Πλήρης περιγραφή

Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς:	Chouliaras, L, Pishva, E, Haapakoski, R, Zsoldos, E, Mahmood, A, Filippini, N, Burrage, J, Mill, J, Kivimäki, M, Lunnon, K, Ebmeier, K
Μορφή:	Journal article
Έκδοση:	Future Medicine 2018

Παρόμοια τεκμήρια

Longitudinal mid-life stroke risk predicts brain structure in the aging whitehall II cohort
ανά: Zsoldos, E, κ.ά.
Έκδοση: (2019)

Allostatic load as a predictor of grey matter volume and white matter integrity in old age: The Whitehall II MRI study
ανά: Zsoldos, E, κ.ά.
Έκδοση: (2018)

Study protocol: the Whitehall II imaging sub-study
ανά: Filippini, N, κ.ά.
Έκδοση: (2014)

Timing of onset of cognitive decline: Results from Whitehall II prospective cohort study
ανά: Singh-Manoux, A, κ.ά.
Έκδοση: (2012)

Timing of onset of cognitive decline: results from Whitehall II prospective cohort study.
ανά: Singh-Manoux, A, κ.ά.
Έκδοση: (2012)

Sub-threshold depressive symptoms and brain structure: A magnetic resonance imaging study within the Whitehall II cohort
ανά: Allan, C, κ.ά.
Έκδοση: (2016)

Multimodal brain-age prediction and cardiovascular risk: the Whitehall II MRI sub-study
ανά: de Lange, A-MG, κ.ά.
Έκδοση: (2020)

Associations between arterial stiffening and brain structure, perfusion and cognition in the Whitehall II Imaging Sub-study: a retrospective cohort study
ανά: Suri, S, κ.ά.
Έκδοση: (2020)

Association of trajectories of depressive symptoms with vascular risk, cognitive function and adverse brain outcomes: The Whitehall II MRI sub-study
ανά: Demnitz, N, κ.ά.
Έκδοση: (2020)

Associations between arterial stiffening and brain structure, perfusion, and cognition in the Whitehall II Imaging Sub-study: A retrospective cohort study.
ανά: Sana Suri, κ.ά.
Έκδοση: (2020-12-01)

Multimodal brain-age prediction and cardiovascular risk: The Whitehall II MRI sub-study
ανά: Ann-Marie G. de Lange, κ.ά.
Έκδοση: (2020-11-01)

Study protocol: the Whitehall II imaging sub-study
ανά: Ebmeier, K
Έκδοση: (2014)

Brain markers of cumulative stress response and allostatic load in the ageing Whitehall II cohort
ανά: Zsoldos, E
Έκδοση: (2017)

Integrating large-scale neuroimaging research datasets: harmonisation of white matter hyperintensity measurements across Whitehall and UK Biobank datasets
ανά: Bordin, V, κ.ά.
Έκδοση: (2021)

Integrating large-scale neuroimaging research datasets: Harmonisation of white matter hyperintensity measurements across Whitehall and UK Biobank datasets
ανά: Valentina Bordin, κ.ά.
Έκδοση: (2021-08-01)

Elucidating distinct molecular signatures of Lewy body dementias
ανά: Joshua Harvey, κ.ά.
Έκδοση: (2023-11-01)

Association of ideal cardiovascular health at age 50 with incidence of dementia: 25 year follow-up of Whitehall II cohort study
ανά: Sabia, S, κ.ά.
Έκδοση: (2019)

Moderate alcohol consumption as a risk factor for adverse brain outcomes and cognitive decline: longitudinal cohort study
ανά: Topiwala, A, κ.ά.
Έκδοση: (2017)

Development and validation of a dementia risk score in the UK Biobank and Whitehall II Cohorts
ανά: Anatürk, M, κ.ά.
Έκδοση: (2023)

Household wealth and the metabolic syndrome in the Whitehall II study.
ανά: Perel, P, κ.ά.
Έκδοση: (2006)

Development and validation of a dementia risk score in the UK Biobank and Whitehall II cohorts
ανά: Mika Kivimäki, κ.ά.
Έκδοση: (2023-10-01)

Height loss and future coronary heart disease in London: the Whitehall II study.
ανά: Batty, G, κ.ά.
Έκδοση: (2011)

Whitehall Study Authors' reply
ανά: Clarke, R, κ.ά.
Έκδοση: (2009)

The reformers’ portraits in Tudor Whitehall
ανά: Sowerby, T
Έκδοση: (2022)

Examining overweight and obesity as risk factors for common mental disorders using fat mass and obesity-associated (FTO) genotype-instrumented analysis: The Whitehall II Study, 1985-2004.
ανά: Kivimäki, M, κ.ά.
Έκδοση: (2011)

Is there an association between work stress and diurnal cortisol patterns? Findings from the Whitehall II study.
ανά: Jing Liao, κ.ά.
Έκδοση: (2013-01-01)

Adiponectin, biomarkers of inflammation and changes in cardiac autonomic function: Whitehall II study
ανά: Christian Stevns Hansen, κ.ά.
Έκδοση: (2017-12-01)

Risk factors for pancreatic cancer mortality: extended follow-up of the original Whitehall Study.
ανά: Batty, G, κ.ά.
Έκδοση: (2009)

Whitehall palace : the official illustrated history /
ανά: Thurley, Simon, 1962-
Έκδοση: (2008)

Integrated care cannot be designed in Whitehall
ανά: Peter Howitt, κ.ά.
Έκδοση: (2012-05-01)

Integrated care cannot be designed in Whitehall
ανά: Peter Howitt, κ.ά.
Έκδοση: (2012-05-01)

Moderate alcohol consumptionmay be a risk factor for adverse brain outcomes and cognitive decline
ανά: Topiwala, A, κ.ά.
Έκδοση: (2017)

Moderate alcohol consumption as a risk factor for adverse brain outcomes and cognitive decline
ανά: Topiwala, A, κ.ά.
Έκδοση: (2017)

Assessing the co-variability of DNA methylation across peripheral cells and tissues: Implications for the interpretation of findings in epigenetic epidemiology.
ανά: Eilis Hannon, κ.ά.
Έκδοση: (2021-03-01)

Modifiable risk factors for prostate cancer mortality in London: forty years of follow-up in the Whitehall study.
ανά: Batty, G, κ.ά.
Έκδοση: (2011)

Overtime work as a predictor of major depressive episode: a 5-year follow-up of the Whitehall II study.
ανά: Marianna Virtanen, κ.ά.
Έκδοση: (2012-01-01)

Modifiable risk factors for prostate cancer mortality in London: forty years of follow-up in the Whitehall study
ανά: David Batty, G, κ.ά.
Έκδοση: (2010)

Physical Activity, Sedentary Behavior, and Long‐Term Changes in Aortic Stiffness: The Whitehall II Study
ανά: Sara Ahmadi‐Abhari, κ.ά.
Έκδοση: (2017-08-01)

Associations between longitudinal trajectories of cognitive and social activities and brain health in old age
ανά: Anaturk, M, κ.ά.
Έκδοση: (2020)

Occupational stress, bullying and resilience in old age.
ανά: Zsoldos, E, κ.ά.
Έκδοση: (2014)