Chemistry-to-gene screens in Caenorhabditis elegans.

Chemistry-to-gene screens in Caenorhabditis elegans.

The nematode worm Caenorhabditis elegans is a genetic model organism linked to an impressive portfolio of fundamental discoveries in biology. This free-living nematode, which can be easily and inexpensively grown in the laboratory, is also a natural vehicle for screening for drugs that are active ag...

Bibliográfalaš dieđut
Váldodahkkit:	Jones, A, Buckingham, S, Sattelle, D
Materiálatiipa:	Journal article
Giella:	English
Almmustuhtton:	2005

Geahča maid

The cys-loop ligand-gated ion channel gene superfamily of the nematode, Caenorhabditis elegans.
Dahkki: Jones, A, et al.
Almmustuhtton: (2008)

Glutamate-gated chloride channels of Haemonchus contortus restore drug sensitivity to ivermectin resistant Caenorhabditis elegans
Dahkki: Glendinning, S, et al.
Almmustuhtton: (2011)

Contributions from Caenorhabditis elegans functional genetics to antiparasitic drug target identification and validation: nicotinic acetylcholine receptors, a case study.
Dahkki: Brown, L, et al.
Almmustuhtton: (2006)

Automated, high-throughput, motility analysis in Caenorhabditis elegans and parasitic nematodes: Applications in the search for new anthelmintics
Dahkki: Steven D. Buckingham, et al.
Almmustuhtton: (2014-12-01)

A novel point mutation in the Caenorhabditis elegans smn-1 gene provides a useful model for investigating Spinal Muscular Atrophy
Dahkki: Sleigh, J, et al.
Almmustuhtton: (2010)

Strategies for automated analysis of C. elegans locomotion.
Dahkki: Buckingham, S, et al.
Almmustuhtton: (2008)

A Cys-loop mutation in the Caenorhabditis elegans nicotinic receptor subunit UNC-63 impairs but does not abolish channel function.
Dahkki: Jones, A, et al.
Almmustuhtton: (2011)

Glutamate-gated chloride channels of Haemonchus contortus restore drug sensitivity to ivermectin resistant Caenorhabditis elegans.
Dahkki: Susan K Glendinning, et al.
Almmustuhtton: (2011-01-01)

Novel alpha7-like nicotinic acetylcholine receptor subunits in the nematode Caenorhabditis elegans.
Dahkki: Mongan, N, et al.
Almmustuhtton: (2002)

A novel Caenorhabditis elegans allele, smn-1(cb131), mimicking a mild form of spinal muscular atrophy, provides a convenient drug screening platform highlighting new and pre-approved compounds.
Dahkki: Sleigh, J, et al.
Almmustuhtton: (2011)

Cloning and developmental expression analysis of ltd-1, the Caenorhabditis elegans homologue of the mouse kyphoscoliosis (ky) gene.
Dahkki: Vargas, J, et al.
Almmustuhtton: (2002)

Gene expression profiling studies on Caenorhabditis elegans dystrophin mutants dys-1(cx-35) and dys-1(cx18).
Dahkki: Towers, P, et al.
Almmustuhtton: (2006)

Deletion of smn-1, the Caenorhabditis elegans ortholog of the spinal muscular atrophy gene, results in locomotor dysfunction and reduced lifespan.
Dahkki: Briese, M, et al.
Almmustuhtton: (2009)

Immunosenescence in Caenorhabditis elegans
Dahkki: Sieun S. Kim, et al.
Almmustuhtton: (2022-11-01)

Gene pathways that delay Caenorhabditis elegans reproductive senescence.
Dahkki: Meng C Wang, et al.
Almmustuhtton: (2014-12-01)

Gene Pathways That Delay Caenorhabditis elegans Reproductive Senescence
Dahkki: Wang, Meng C., et al.
Almmustuhtton: (2014)

Counting mutagenized genomes and optimizing genetic screens in Caenorhabditis elegans.
Dahkki: Shai Shaham
Almmustuhtton: (2007-01-01)

Medical significance of Caenorhabditis elegans.
Dahkki: Aboobaker, A, et al.
Almmustuhtton: (2000)

Vitellogenins - Yolk Gene Function and Regulation in Caenorhabditis elegans
Dahkki: Marcos Francisco Perez, et al.
Almmustuhtton: (2019-08-01)

Regulatory elements of <it>Caenorhabditis elegans</it> ribosomal protein genes
Dahkki: Sleumer Monica C, et al.
Almmustuhtton: (2012-08-01)

Antimicrobial peptides in Caenorhabditis elegans
Dahkki: A Bogaerts, et al.
Almmustuhtton: (2010-01-01)

Transcriptional adaptation in Caenorhabditis elegans
Dahkki: Vahan Serobyan, et al.
Almmustuhtton: (2020-01-01)

Endogenous control of stochastic gene expression in the development of Caenorhabditis elegans
Dahkki: Ji, Ni, Ph. D. Massachusetts Institute of Technology
Almmustuhtton: (2013)

Untwisting the Caenorhabditis elegans embryo
Dahkki: Ryan Patrick Christensen, et al.
Almmustuhtton: (2015-12-01)

Convenient screening of the reproductive toxicity of favipiravir and antiviral drugs in Caenorhabditis elegans
Dahkki: Kimiyasu Shiraki, et al.
Almmustuhtton: (2024-08-01)

Parallel-Channel Electrotaxis and Neuron Screening of <em>Caenorhabditis elegans</em>
Dahkki: Khaled Youssef, et al.
Almmustuhtton: (2020-08-01)

A Genetic Screen for Mutants with Supersized Lipid Droplets in Caenorhabditis elegans
Dahkki: Shiwei Li, et al.
Almmustuhtton: (2016-08-01)

Necrotic Neurodegeneration in Caenorhabditis Elegans
Dahkki: Keli Xu, et al.
Almmustuhtton: (2001-01-01)

Nucleologenesis in the Caenorhabditis elegans embryo.
Dahkki: Darina Korčeková, et al.
Almmustuhtton: (2012-01-01)

Genetics of aging in Caenorhabditis elegans.
Dahkki: Adam Antebi
Almmustuhtton: (2007-09-01)

Immunoprecipitation of Proteins in Caenorhabditis elegans
Dahkki: Kevin Chan, et al.
Almmustuhtton: (2015-04-01)

The TRiC/CCT chaperone is implicated in Alzheimer's disease based on patient GWAS and an RNAi screen in Aβ-expressing Caenorhabditis elegans.
Dahkki: Eleonora Khabirova, et al.
Almmustuhtton: (2014-01-01)

Gene expression modifications by temperature-toxicants interactions in Caenorhabditis elegans.
Dahkki: Ana Viñuela, et al.
Almmustuhtton: (2011-01-01)

Temporal dynamics of gene expression in heat-stressed Caenorhabditis elegans.
Dahkki: Katharina Jovic, et al.
Almmustuhtton: (2017-01-01)

Genomic identification and functional analysis of essential genes in Caenorhabditis elegans
Dahkki: Shicheng Yu, et al.
Almmustuhtton: (2018-12-01)

Genomic Identification and Functional Characterization of Essential Genes in Caenorhabditis elegans
Dahkki: Zhaozhao Qin, et al.
Almmustuhtton: (2018-03-01)

Genetic and molecular analysis of synthetic multivulva genes in Caenorhabditis elegans
Dahkki: Thomas, Jeffrey H. (Jeffrey Howard), 1967-
Almmustuhtton: (2008)

Mechanisms of iron metabolism in Caenorhabditis elegans
Dahkki: Elizabeth A Leibold, et al.
Almmustuhtton: (2014-05-01)

Chemically defined medium and <it>Caenorhabditis elegans</it>
Dahkki: Kozak Elena, et al.
Almmustuhtton: (2003-10-01)

Functional Screening of Parkinson’s Disease Susceptibility Genes to Identify Novel Modulators of α-Synuclein Neurotoxicity in Caenorhabditis elegans
Dahkki: Roman Vozdek, et al.
Almmustuhtton: (2022-04-01)