Different pathways of colorectal carcinogenesis and their clinical pictures.

An entertaining debate in cancer genetics concerns the relative importance of selection for a growth advantage and genomic instability in tumorigenesis. Below, I present evidence that shows that selection is more important, particularly in the early stages of tumorigenesis, but that genomic instabil...

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Autore principale: Tomlinson, I
Natura: Journal article
Lingua:English
Pubblicazione: 2000