Different pathways of colorectal carcinogenesis and their clinical pictures.

An entertaining debate in cancer genetics concerns the relative importance of selection for a growth advantage and genomic instability in tumorigenesis. Below, I present evidence that shows that selection is more important, particularly in the early stages of tumorigenesis, but that genomic instabil...

ver descrição completa

Detalhes bibliográficos
Autor principal: Tomlinson, I
Formato: Journal article
Idioma:English
Publicado em: 2000