5-HT2C receptor activation decreases appetite and body weight in obese subjects.

We studied the effect of 2 weeks administration of the 5-HT2C receptor agonist, m-chlorophenylpiperazine (mCPP), on appetite and body weight in 18 moderately obese subjects in a double-blind, placebo-controlled trial, mCPP caused a small but significant (0.75 kg) reduction in body weight and in subj...

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Bibliographic Details
Main Authors: Sargent, P, Sharpley, A, Williams, C, Goodall, E, Cowen, P
Format: Journal article
Language:English
Published: 1997