DNA methylation protects hematopoietic stem cell multipotency from myeloerythroid restriction.

DNA methylation is a dynamic epigenetic mark that undergoes extensive changes during differentiation of self-renewing stem cells. However, whether these changes are the cause or consequence of stem cell fate remains unknown. Here, we show that alternative functional programs of hematopoietic stem ce...

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Hlavní autoři: Bröske, A, Vockentanz, L, Kharazi, S, Huska, MR, Mancini, E, Scheller, M, Kuhl, C, Enns, A, Prinz, M, Jaenisch, R, Nerlov, C, Leutz, A, Andrade-Navarro, M, Jacobsen, SE, Rosenbauer, F
Médium: Journal article
Jazyk:English
Vydáno: 2009