DNA methylation protects hematopoietic stem cell multipotency from myeloerythroid restriction.

DNA methylation is a dynamic epigenetic mark that undergoes extensive changes during differentiation of self-renewing stem cells. However, whether these changes are the cause or consequence of stem cell fate remains unknown. Here, we show that alternative functional programs of hematopoietic stem ce...

Descripción completa

Detalles Bibliográficos
Autores principales: Bröske, A, Vockentanz, L, Kharazi, S, Huska, MR, Mancini, E, Scheller, M, Kuhl, C, Enns, A, Prinz, M, Jaenisch, R, Nerlov, C, Leutz, A, Andrade-Navarro, M, Jacobsen, SE, Rosenbauer, F
Formato: Journal article
Lenguaje:English
Publicado: 2009