Comparative analysis of three-dimensional chromosomal architecture identifies a novel fetal hemoglobin regulatory element.

Comparative analysis of three-dimensional chromosomal architecture identifies a novel fetal hemoglobin regulatory element.

Chromatin structure is tightly intertwined with transcription regulation. Here we compared the chromosomal architectures of fetal and adult human erythroblasts and found that, globally, chromatin structures and compartments A/B are highly similar at both developmental stages. At a finer scale, we de...

Mô tả đầy đủ

Chi tiết về thư mục
Những tác giả chính:	Huang, P, Keller, C, Giardine, B, Grevet, J, Davies, J, Hughes, J, Kurita, R, Nakamura, Y, Hardison, R, Blobel, G
Định dạng:	Journal article
Ngôn ngữ:	English
Được phát hành:	Cold Spring Harbour Laboratory Press 2017

Những quyển sách tương tự

Establishment of regulatory elements during erythro-megakaryopoiesis identifies hematopoietic lineage-commitment points
Bằng: Elisabeth F. Heuston, et al.
Được phát hành: (2018-05-01)

Comparative genome analysis delimits a chromosomal domain and identifies key regulatory elements in the alpha globin cluster.
Bằng: Flint, J, et al.
Được phát hành: (2001)

Base-editing-mediated dissection of a γ-globin cis-regulatory element for the therapeutic reactivation of fetal hemoglobin expression
Bằng: Panagiotis Antoniou, et al.
Được phát hành: (2022-11-01)

CLIMB: High-dimensional association detection in large scale genomic data
Bằng: Hillary Koch, et al.
Được phát hành: (2022-11-01)

Multiple Structural Maintenance of Chromosome Complexes at Transcriptional Regulatory Elements
Bằng: Dowen, Jill M., et al.
Được phát hành: (2014)

Transcriptional regulators of fetal hemoglobin
Bằng: Gabriela Pereira dos Santos, et al.
Được phát hành: (2024-11-01)

Hereditary persistence of fetal hemoglobin
Bằng: Dharmesh Chandra Sharma, et al.
Được phát hành: (2020-01-01)

POGZ Is Required for Silencing Mouse Embryonic β-like Hemoglobin and Human Fetal Hemoglobin Expression
Bằng: Bjorg Gudmundsdottir, et al.
Được phát hành: (2018-06-01)

Epigenetic Modulations on the Fetal Hemoglobin Induction
Bằng: Saeid Kaviani, et al.
Được phát hành: (2012-03-01)

Epigenetic modulations on the fetal hemoglobin induction
Bằng: Najmaldin Saki, et al.
Được phát hành: (2012-01-01)

Sickle cell disease and fetal hemoglobin
Bằng: Alicia Rivera
Được phát hành: (2018-01-01)

3′HS1 CTCF binding site in human β-globin locus regulates fetal hemoglobin expression
Bằng: Pamela Himadewi, et al.
Được phát hành: (2021-09-01)

Induction of Fetal Hemoglobin by Introducing Natural Hereditary Persistence of Fetal Hemoglobin Mutations in the γ-Globin Gene Promoters for Genome Editing Therapies for β-Thalassemia
Bằng: Dian Lu, et al.
Được phát hành: (2022-05-01)

CTCF and transcription influence chromatin structure re-configuration after mitosis
Bằng: Haoyue Zhang, et al.
Được phát hành: (2021-08-01)

A new target for fetal hemoglobin reactivation
Bằng: Angela Rivers, et al.
Được phát hành: (2019-12-01)

Identification of novel HPFH-like mutations by CRISPR base editing that elevate the expression of fetal hemoglobin
Bằng: Nithin Sam Ravi, et al.
Được phát hành: (2022-02-01)

Genetics of fetal hemoglobin in Tanzanian and British patients with sickle cell anemia.
Bằng: Makani, J, et al.
Được phát hành: (2011)

Exploiting genetic variation to uncover rules of transcription factor binding and chromatin accessibility
Bằng: Vivek Behera, et al.
Được phát hành: (2018-02-01)

Fetal hemoglobin does not inhibit Plasmodium falciparum growth
Bằng: Natasha M. Archer, et al.
Được phát hành: (2019-07-01)

The Emerging role of Immunomodulatory Agents in Fetal Hemoglobin Induction
Bằng: Ali Dehghani-Fard, et al.
Được phát hành: (2015-10-01)

The Emerging role of Immunomodulatory Agents in Fetal Hemoglobin Induction
Bằng: Ali Dehghani Fard, et al.
Được phát hành: (2012-10-01)

Reactivation of fetal hemoglobin in thalassemia and sickle cell disease
Bằng: Sandro Eridani, et al.
Được phát hành: (2014-09-01)

Reference intervals for acetylated fetal hemoglobin in healthy newborns
Bằng: Renata Paleari, et al.
Được phát hành: (2014-09-01)

Oxidative stress in preeclampsia and the role of free fetal hemoglobin
Bằng: Stefan Rocco Hansson, et al.
Được phát hành: (2015-01-01)

Fetal hemoglobin and hemolysis markers in sickle cell anemia
Bằng: Marina Pereira Colella, et al.
Được phát hành: (2015-06-01)

Impact of fetal hemoglobin on micronutrients in sickle cell anemia
Bằng: Mathias Abiodun Emokpae, et al.
Được phát hành: (2015-01-01)

Genome wide association study of fetal hemoglobin in sickle cell anemia in Tanzania
Bằng: Mtatiro, SN, et al.
Được phát hành: (2014)

Agentes indutores da síntese de hemoglobina fetal Fetal hemoglobin inducing factors
Bằng: Maria Stella Figueiredo
Được phát hành: (2007-09-01)

Genome editing of HBG1 and HBG2 to induce fetal hemoglobin
Bằng: Jean-Yves Métais, et al.
Được phát hành: (2019-11-01)

Fetal Hemoglobin is Associated with Peripheral Oxygen Saturation in Sickle Cell Disease in Tanzania
Bằng: Siana Nkya, et al.
Được phát hành: (2017-09-01)

Fetal hemoglobin is associated with peripheral oxygen saturation in sickle cell disease in Tanzania.
Bằng: Nkya, S, et al.
Được phát hành: (2017)

Intergenic variants of HBS1L-MYB are responsible for a major quantitative trait locus on chromosome 6q23 influencing fetal hemoglobin levels in adults.
Bằng: Thein, S, et al.
Được phát hành: (2007)

Identification of small molecule agonists of fetal hemoglobin expression for the treatment of sickle cell disease.
Bằng: Jian-Ping Yang, et al.
Được phát hành: (2024-01-01)

Loss of chromosome Y in regulatory T cells
Bằng: Jonas Mattisson, et al.
Được phát hành: (2024-03-01)

A cellular reporter system to evaluate endogenous fetal hemoglobin induction and screen for therapeutic compounds
Bằng: Thijs C. J. Verheul, et al.
Được phát hành: (2024-08-01)

A point about fetal hemoglobin determination in cord blood
Bằng: E Yilgör, et al.
Được phát hành: (1974-07-01)

FETAL HEMOGLOBIN DETERMINATIONS IN THE NEWBORN BY THE SINGER AND ACID ELUTION METHODS
Bằng: I Ozalp, et al.
Được phát hành: (1964-04-01)

ROLE OF STEM CELL FACTOR IN THE REACTIVATION OF HUMAN FETAL HEMOGLOBIN
Bằng: Ugo Testa, et al.
Được phát hành: (2009-06-01)

ROLE OF STEM CELL FACTOR IN THE REACTIVATION OF HUMAN FETAL HEMOGLOBIN
Bằng: Marco Gabbianelli, et al.
Được phát hành: (2009-11-01)

Stability of fetal hemoglobin levels in patients receiving metformin therapy
Bằng: Mohamed-Rachid Boulassel, et al.
Được phát hành: (2018-10-01)